IgA Nephropathy Insights

IgA nephropathy involves the deposition of IgA immune complexes in the kidneys, causing inflammation and potential damage. Symptoms include hematuria, proteinuria, and edema. The disease progresses slowly over years, leading to complications like high blood pressure and chronic kidney disease.

Treatment typically involves medications such as ACE inhibitors and ARBs to manage blood pressure and protein loss, along with corticosteroids to reduce inflammation. Lifestyle changes, including diet modifications and smoking cessation, are also recommended. While there is no cure, these interventions can help slow disease progression and prevent complications, as noted in ongoing research into new treatments (Aubron et al., 2025).